| 2022-02-08 15:00:33February 8, 2022 | Exeter City vs Leyton Orient | 15:00:333:00 pm | League 2 | 2021/22 | St James Park, Exeter |
| 2021-08-14 15:00:16August 14, 2021 | Leyton Orient vs Exeter City | 3 - 0 | League 2 | 2021/22 | Brisbane Road |
| 2021-03-06 13:00:25March 6, 2021 | Exeter City vs Leyton Orient | 4 - 0 | League 2 | 2020/21 | St James Park, Exeter |
| 2020-10-27 19:00:22October 27, 2020 | Leyton Orient vs Exeter City | 1 - 1 | League 2 | 2020/21 | Brisbane Road |
| 2020-04-25 15:00:39April 25, 2020 | Leyton Orient vs Exeter City | 15:00:39Postponed | League 2 | 2019/20 | Brisbane Road |
| 2019-09-14 15:00:20September 14, 2019 | Exeter City vs Leyton Orient | 2 - 2 | League 2 | 2019/20 | St James Park, Exeter |
| 2017-01-02 15:00:04January 2, 2017 | Exeter City vs Leyton Orient | 4 - 0 | League 2 | 2016/17 | St James Park, Exeter |
| 2016-11-22 19:45:03November 22, 2016 | Leyton Orient vs Exeter City | 0 - 1 | League 2 | 2016/17 | Brisbane Road |
| 2016-01-16 15:00:58January 16, 2016 | Leyton Orient vs Exeter City | 1 - 3 | League 2 | 2015/16 | Brisbane Road |
| 2015-09-05 15:00:18September 5, 2015 | Exeter City vs Leyton Orient | 4 - 0 | League 2 | 2015/16 | St James Park, Exeter |
| 2012-04-09 15:00:16April 9, 2012 | Exeter City vs Leyton Orient | 3 - 0 | League 1 | 2011/12 | St James Park, Exeter |
| 2011-12-10 15:00:01December 10, 2011 | Leyton Orient vs Exeter City | 3 - 0 | League 1 | 2011/12 | Brisbane Road |
| 2011-04-16 15:00:56April 16, 2011 | Exeter City vs Leyton Orient | 2 - 1 | League 1 | 2010/11 | St James Park, Exeter |
| 2010-08-28 15:00:44August 28, 2010 | Leyton Orient vs Exeter City | 3 - 0 | League 1 | 2010/11 | Brisbane Road |
| 2010-04-10 15:00:00April 10, 2010 | Exeter City vs Leyton Orient | 0 - 0 | League 1 | 2009/10 | St James Park, Exeter |
| 2009-09-12 15:00:55September 12, 2009 | Leyton Orient vs Exeter City | 1 - 1 | League 1 | 2009/10 | Brisbane Road |
| 2003-03-08 15:00:20March 8, 2003 | Leyton Orient vs Exeter City | 1 - 1 | Division 3 | 2002/03 | Brisbane Road |
| 2002-09-21 15:00:05September 21, 2002 | Exeter City vs Leyton Orient | 1 - 0 | Division 3 | 2002/03 | St James Park, Exeter |
| 2002-04-13 15:00:34April 13, 2002 | Leyton Orient vs Exeter City | 1 - 1 | Division 3 | 2001/02 | Brisbane Road |
| 2001-11-24 15:00:37November 24, 2001 | Exeter City vs Leyton Orient | 0 - 0 | Division 3 | 2001/02 | St James Park, Exeter |
| 2001-01-13 15:00:22January 13, 2001 | Exeter City vs Leyton Orient | 2 - 3 | Division 3 | 2000/01 | St James Park, Exeter |
| 2000-08-28 15:00:01August 28, 2000 | Leyton Orient vs Exeter City | 2 - 1 | Division 3 | 2000/01 | Brisbane Road |
| 2000-02-08 19:45:02February 8, 2000 | Leyton Orient vs Exeter City | 4 - 1 | Division 3 | 1999/00 | Brisbane Road |
| 2000-01-08 15:00:50January 8, 2000 | Exeter City vs Leyton Orient | 1 - 3 | Division 3 | 1999/00 | St James Park, Exeter |
| 1999-04-05 15:00:10April 5, 1999 | Exeter City vs Leyton Orient | 1 - 1 | Division 3 | 1998/99 | St James Park, Exeter |
| 1998-10-09 19:45:30October 9, 1998 | Leyton Orient vs Exeter City | 2 - 0 | Division 3 | 1998/99 | Brisbane Road |
| 1998-01-31 15:00:42January 31, 1998 | Exeter City vs Leyton Orient | 2 - 2 | Division 3 | 1997/98 | St James Park, Exeter |
| 1997-09-13 15:00:59September 13, 1997 | Leyton Orient vs Exeter City | 1 - 0 | Division 3 | 1997/98 | Brisbane Road |
| 1997-02-01 15:00:52February 1, 1997 | Leyton Orient vs Exeter City | 1 - 1 | Division 3 | 1996/97 | Brisbane Road |
| 1996-11-09 15:00:33November 9, 1996 | Exeter City vs Leyton Orient | 3 - 2 | Division 3 | 1996/97 | St James Park, Exeter |
| 1995-12-09 15:00:11December 9, 1995 | Leyton Orient vs Exeter City | 0 - 3 | Division 3 | 1995/96 | Brisbane Road |
| 1995-09-23 15:00:16September 23, 1995 | Exeter City vs Leyton Orient | 15:00:163:00 pm | Division 3 | 1995/96 | St James Park, Exeter |
| 1994-04-23 15:00:18April 23, 1994 | Exeter City vs Leyton Orient | 15:00:183:00 pm | D2 | 1993/94 | St James Park, Exeter |
| 1993-12-14 19:45:30December 14, 1993 | Exeter City vs Leyton Orient | 2 - 2 | FA Cup | 1993/94 | St James Park, Exeter |
| 1993-12-04 15:00:56December 4, 1993 | Leyton Orient vs Exeter City | 1 - 1 | FA Cup | 1993/94 | Brisbane Road |
| 1993-11-06 15:00:46November 6, 1993 | Leyton Orient vs Exeter City | 1 - 1 | D2 | 1993/94 | Brisbane Road |
| 1993-01-23 15:00:28January 23, 1993 | Leyton Orient vs Exeter City | 5 - 0 | D2 | 1992/93 | Brisbane Road |
| 1992-09-19 15:00:52September 19, 1992 | Exeter City vs Leyton Orient | 1 - 0 | D2 | 1992/93 | St James Park, Exeter |
| 1987-11-14 15:00:49November 14, 1987 | Leyton Orient vs Exeter City | 2 - 0 | FA Cup | 1987/88 | Brisbane Road |
Leyton Orient
