| 2000-08-12 15:00:06August 12, 2000 | Exeter City vs Cardiff City | 1 - 2 | Division 3 | St James Park, Exeter |
| 2000-08-19 15:00:36August 19, 2000 | Darlington vs Exeter City | 1 - 1 | Division 3 | Darlington Arena |
| 2000-08-22 19:45:25August 22, 2000 | Swindon Town vs Exeter City | 1 - 1 | Worthington Cup | County Ground, Swindon |
| 2000-08-26 15:00:51August 26, 2000 | Exeter City vs Hartlepool United | 1 - 1 | Division 3 | St James Park, Exeter |
| 2000-08-28 15:00:01August 28, 2000 | Leyton Orient vs Exeter City | 2 - 1 | Division 3 | Brisbane Road |
| 2000-09-02 15:00:55September 2, 2000 | Exeter City vs Mansfield Town | 0 - 0 | Division 3 | St James Park, Exeter |
| 2000-09-05 19:45:41September 5, 2000 | Exeter City vs Swindon Town | 1 - 2 | Worthington Cup | St James Park, Exeter |
| 2000-09-09 15:00:13September 9, 2000 | Macclesfield vs Exeter City | 0 - 2 | Division 3 | Moss Rose, Macclesfield |
| 2000-09-12 19:45:41September 12, 2000 | Barnet vs Exeter City | 1 - 1 | Division 3 | Underhill, Barnet |
| 2000-09-16 15:00:02September 16, 2000 | Exeter City vs York City | 3 - 1 | Division 3 | St James Park, Exeter |
| 2000-09-23 15:00:19September 23, 2000 | Carlisle United vs Exeter City | 0 - 1 | Division 3 | Brunton Park, Carlisle |
| 2000-09-30 15:00:32September 30, 2000 | Exeter City vs Cheltenham Town | 0 - 2 | Division 3 | St James Park, Exeter |
| 2000-10-06 19:45:42October 6, 2000 | Shrewsbury Town vs Exeter City | 2 - 0 | Division 3 | Gay Meadow, Shrewsbury |
| 2000-10-14 15:00:25October 14, 2000 | Exeter City vs Chesterfield FC | 1 - 1 | Division 3 | St James Park, Exeter |
| 2000-10-17 19:45:59October 17, 2000 | Exeter City vs Hull City | 0 - 1 | Division 3 | St James Park, Exeter |
| 2000-10-21 15:00:11October 21, 2000 | Kidderminster Harriers vs Exeter City | 0 - 0 | Division 3 | Aggborough, Kidderminster |
| 2000-10-24 19:45:01October 24, 2000 | Southend United vs Exeter City | 1 - 1 | Division 3 | Roots Hall, Southend |
| 2000-10-28 15:00:33October 28, 2000 | Exeter City vs Rochdale | 0 - 1 | Division 3 | St James Park, Exeter |
| 2000-11-04 15:00:43November 4, 2000 | Halifax Town vs Exeter City | 3 - 1 | Division 3 | Shay The, Halifax |
| 2000-11-11 15:00:25November 11, 2000 | Exeter City vs Scunthorpe United | 2 - 1 | Division 3 | St James Park, Exeter |
| 2000-11-18 15:00:21November 18, 2000 | Walsall vs Exeter City | 4 - 0 | FA Cup | Bescot, Walsall |
| 2000-11-25 15:00:20November 25, 2000 | Lincoln City vs Exeter City | 3 - 1 | Division 3 | Sincil Bank, Lincoln |
| 2000-12-02 15:00:26December 2, 2000 | Exeter City vs Plymouth Argyle | 0 - 2 | Division 3 | St James Park, Exeter |
| 2000-12-05 19:45:07December 5, 2000 | Wycombe Wanderers vs Exeter City | 1 - 0 | LDV | Adams Park, Wycombe |
| 2000-12-09 15:00:05December 9, 2000 | Chesterfield FC vs Exeter City | 2 - 0 | Division 3 | Saltergate, Chesterfield |
| 2000-12-16 15:00:14December 16, 2000 | Blackpool vs Exeter City | 3 - 0 | Division 3 | Bloomfield Road, Blackpool |
| 2000-12-22 19:45:56December 22, 2000 | Brighton & Hove Albion vs Exeter City | 2 - 0 | Division 3 | Withdean, Brighton |
| 2000-12-26 15:00:37December 26, 2000 | Exeter City vs Torquay United | 1 - 1 | Division 3 | St James Park, Exeter |
| 2001-01-01 15:00:27January 1, 2001 | Cardiff City vs Exeter City | 6 - 1 | Division 3 | Ninian Park, Cardiff |
| 2001-01-06 15:00:49January 6, 2001 | Hartlepool United vs Exeter City | 2 - 0 | Division 3 | Victoria Park, Hartlepool |
| 2001-01-13 15:00:22January 13, 2001 | Exeter City vs Leyton Orient | 2 - 3 | Division 3 | St James Park, Exeter |
| 2001-01-20 15:00:04January 20, 2001 | Torquay United vs Exeter City | 2 - 1 | Division 3 | Plainmoor, Torquay |
| 2001-01-27 15:00:06January 27, 2001 | Exeter City vs Brighton & Hove Albion | 1 - 0 | Division 3 | St James Park, Exeter |
| 2001-02-02 19:45:46February 2, 2001 | Mansfield Town vs Exeter City | 1 - 1 | Division 3 | Field Mill, Mansfield |
| 2001-02-10 15:00:43February 10, 2001 | Exeter City vs Macclesfield | 0 - 0 | Division 3 | St James Park, Exeter |
| 2001-02-17 15:00:45February 17, 2001 | York City vs Exeter City | 0 - 3 | Division 3 | Bootham Crescent, York |
| 2001-02-20 19:45:08February 20, 2001 | Exeter City v Barnet | 1 - 0` | Division 3 | St James Park, Exeter |
| 2001-02-24 19:45:20February 24, 2001 | Exeter City v Carlisle Utd | 1 - 0 | Division 3 | St James Park, Exeter |
| 2001-03-03 15:00:46March 3, 2001 | Cheltenham Town vs Exeter City | 1 - 0 | Division 3 | Whaddon Road, Cheltenham |
| 2001-03-10 15:00:20March 10, 2001 | Exeter City vs Shrewsbury Town | 1 - 0 | Division 3 | St James Park, Exeter |
| 2001-03-17 15:00:25March 17, 2001 | Hull City vs Exeter City | 2 - 1 | Division 3 | Boothferry Park, Hull |
| 2001-03-24 15:00:22March 24, 2001 | Exeter City vs Kidderminster Harriers | 2 - 1 | Division 3 | St James Park, Exeter |
| 2001-03-27 19:45:59March 27, 2001 | Exeter City vs Darlington | 1 - 1 | Division 3 | St James Park, Exeter |
| 2001-03-31 15:00:27March 31, 2001 | Exeter City vs Blackpool | 2 - 0 | Division 3 | St James Park, Exeter |
| 2001-04-07 15:00:34April 7, 2001 | Plymouth Argyle vs Exeter City | 1 - 0 | Division 3 | Home Park, Plymouth |
| 2001-04-14 15:00:57April 14, 2001 | Exeter City vs Southend United | 2 - 2 | Division 3 | St James Park, Exeter |
| 2001-04-16 15:00:12April 16, 2001 | Rochdale vs Exeter City | 3 - 0 | Division 3 | Spotland, Rochdale |
| 2001-04-21 15:00:56April 21, 2001 | Exeter City vs Halifax Town | 0 - 0 | Division 3 | St James Park, Exeter |
| 2001-04-28 15:00:32April 28, 2001 | Scunthorpe United vs Exeter City | 0 - 2 | Division 3 | Glanford Park, Scunthorpe |
| 2001-05-05 15:00:01May 5, 2001 | Exeter City vs Lincoln City | 0 - 0 | Division 3 | St James Park, Exeter |
Exeter City
